2,6-Dichloropurine

Product Name: 2,6-Dichloropurine
CAS No.: 5451-40-1
Chemical Name: 2,6-Dichloropurine
Synonyms: 2,6-DICHLORO-9H-PURINE;2,6-dichloro-7H-purine;2,6-dichloro-1H-purine;NSC 18395;Dichloropurine;6-Dichloropurine;2,6-DICHLOROPURINE;Cefepime Intermediate;2,6-Dichloropurine>2,6-Dichloropurine.97%
CBNumber: CB1720642
Molecular Formula: C5H2Cl2N4
Formula Weight: 189
MOL File: 5451-40-1.mol

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2,6-Dichloropurine Property

Melting point:: 185-195 °C (dec.) (lit.)
Boiling point:: 310.62°C (rough estimate)
Density: 1.7265 (rough estimate)
refractive index: 1.6300 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble
form: Crystalline Powder
pka: 5.22±0.20(Predicted)
color: White to yellow
Water Solubility: soluble
BRN: 9354
InChIKey: RMFWVOLULURGJI-UHFFFAOYSA-N
CAS DataBase Reference: 5451-40-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-22
Safety Statements: 22-24/25-37/39-26-36
RIDADR: UN2811
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D73103
Product name: 2,6-Dichloropurine
Purity: 97%
Packaging: 1g
Price: $17.48
Updated: 2024/03/01

Sigma-Aldrich

Product number: D73103
Product name: 2,6-Dichloropurine
Purity: 97%
Packaging: 5g
Price: $83.2
Updated: 2024/03/01

TCI Chemical

Product number: D2470
Product name: 2,6-Dichloropurine
Purity: >97.0%(HPLC)(T)
Packaging: 1g
Price: $24
Updated: 2024/03/01

TCI Chemical

Product number: D2470
Product name: 2,6-Dichloropurine
Purity: >97.0%(HPLC)(T)
Packaging: 5g
Price: $60
Updated: 2024/03/01

Alfa Aesar

Product number: B21289
Product name: 2,6-Dichloropurine, 97%
Packaging: 1g
Price: $76.65
Updated: 2024/03/01

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2,6-Dichloropurine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Suzuki-Miyaura cross-coupling between halopurines and arylboronic acids in water-acetonitrile.1

Uses

2,6-Dichloropurine is used in the synthesis of 2,6-diamino-substituted purine derivatives as potential cardiomyogenesis inducing agents.

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 404, 1958 DOI: 10.1021/ja01535a040

Purification Methods

It can be recrystallised from 150 parts of boiling H2O and dried at 100o to constant weight. It is soluble in EtOAc. The HgCl2 salt separates from EtOH solution. UV: max 275nm ( 8.9K) at pH 1; and 280nm ( 8.5K) at pH 11 [Elion & Hitchings J Am Chem Soc 78 3508 1956, Schaeffer & Thomas J Am Chem Soc 80 3738 1958, Beaman & Robins J Appl Chem (London) 12 432 1962, Montgomery J Am Chem Soc 78 1928 1956]. [Beilstein 26 III/IV 1747.]

2,6-Dichloropurine Preparation Products And Raw materials

Raw materials

Preparation Products

Cladribine 2,6-Dichloro-7-methylpurine

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2,6-Dichloropurine Suppliers

Americas 1 Belgium 1 Canada 3 China 441 Europe 3 France 1 Germany 7 India 16 Italy 1 Japan 3 Poland 1 Russia 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 20 United States 64 Global 569

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10194
Advantage: 62

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10658
Advantage: 60

BOC Sciences

Tel: +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19743
Advantage: 58

Accela ChemBio Inc.

Tel: (+1)-858-699-3322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 19965
Advantage: 58

Standardpharm Co. Ltd.

Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Country: United States
ProdList: 14336
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81215950 4000-868-328
Email: customer@uwalab.com
Country: United States
ProdList: 10413
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63711
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

Aceschem Inc.

Tel: +1-817863-6948 +1-（817）863-6948
Email: sales@aceschem.com
Country: United States
ProdList: 19639
Advantage: 58

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View Lastest Price from 2,6-Dichloropurine manufacturers

Hebei Dangtong Import and export Co LTD

Product: 2,6-Dichloropurine 5451-40-1
Price: US $455.00-440.00/kg
Min. Order: 10kg
Purity: 99%
Supply Ability: 100Tons
Release date: 2023-03-03

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: 2,6-Dichloropurine 5451-40-1
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 99
Supply Ability: 20tons
Release date: 2024-02-06

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: 2,6-Dichloropurine 5451-40-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.91%
Supply Ability: 200000
Release date: 2024-04-19

5451-40-1, 2,6-DichloropurineRelated Search:

Allopurinol 2',4'-Dichloroacetophenone 1,2-Dichloroethane Dichloroethane Adenine 2,6-DICHLOROPURINE-2'-DEOXYRIBOSIDE 2,6-Dichloropurine-9--D-riboside,2,6-Dichloropurine-9-b-D-riboside,2,6-DICHLOROPURINE RIBO,2,6-DICHLOROPURINE-9-BETA-D-RIBOSIDE,2,6-DICHLOROPURINE RIBOSIDE 2,6-dichloro-9-(1-methylethyl)-9H-purine 2,6,8-TRICHLOROPURINE 2,6-Dichloro-7-methylpurine DRB Cefepime Purine 2,6-dichloro-9-cyclopentyl-9H-purine 9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE 2,6-DICHLORO-9-(2-DEOXY-3,5,DI-O-(4-METHYLBENZOYL-BETA-D-ERYTHROPENTOFURANOSYL)-9H-PURINE) 2,6-DICHLORO-9-METHYL-9H-PURINE 2,6,8-TRICHLORO-7-METHYLPURINE

2,6-DICHLORO-9H-PURINE

2,6-DICHLOROPURINE

2,6-Dichloropurine.97%

2,6-dichloro-1H-purine

1H-Purine, 2,6-dichloro-

Dichloropurine

Cefepime Intermediate

2,6-dichloro-7H-purine

9H-Purine, 2,6-dichloro-

6-Dichloropurine

NSC 18395

2,6-Dichloropurine&gt

2,6-Dichloropurine USP/EP/BP

5451-40-1

2001-2-5

5451-41-0

C5H2ClN4

HETERO CHLORIDE

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Purines

Building Blocks

Chemical Synthesis

Halogenated Heterocycles

Heterocyclic Building Blocks

Intermediates & Fine Chemicals

Pharmaceuticals

Nucleotides

Fused Ring Systems

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

PurinesHeterocyclic Building Blocks

Biochemistry

Nucleobases and their analogs

Nucleosides, Nucleotides & Related Reagents

Nucleic acids

Bases & Related Reagents

Pyridines, Pyrimidines, Purines and Pteredines

Halides

Purine

Nucleotides and Nucleosides

Purines

FINE Chemical & INTERMEDIATES

Starting Raw Materials & Intermediates

Heterocycles

5451-40-1